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KMID : 0383820160790040302
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Tuberculosis and Respiratory Diseases
2016 Volume.79 No. 4 p.302 ~ p.306
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Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome
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Lee Seung-Hyun
Kim Jae-Hyung
Park Se-Jin
Won Chang-Youn
Lee Joo-Hyun
Yi Seong-Yoon
Park Hye-Kyeong
Chang Sun-Hee
Jung Hoon
Lee Sung-Soon
Koo Hyeon-Kyoung
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Abstract
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Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS.
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KEYWORD
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Myelodysplastic Syndromes, Vasculitis, Leukocytoclastic, Cutaneous, Paraneoplastic Syndromes, Pneumonia
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